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Extracellular ATP is released from live cells in controlled conditions, as well as dying cells in inflammatory conditions, and, thereby, regulates T cell responses, including T helper 17 cell (Th17) induction
Commensal microbiota-dependent ATP release mediates the enhanced T helper 17 cell (Th17) development in the small intestinal lamina propria
Administration of ATP leads to a marked increase in lamina propria T helpe…