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The vitamin D / vitamin D receptor (VDR) pathway has been increasingly recognized for its potential therapeutic role in non-alcoholic fatty liver disease (NAFLD).
Vitamin D3 is metabolized in the liver to 25-hydroxyvitamin D3 (25(OH)D3) and then in the kidney to 1,25-dihydroxyvitamin D3 (1,25(OH)2D3). The biological effects of 1,25(OH)2D3 are relevant to the pathogenesis and progression of [Non-Alcoholic Fatty Liver Disease (NAFLD) / Metabolic dysfunction-associated fatty liver disease (MAFLD)](brain://0_T4lKylP0CsXkdsY4Si…