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Metformin is widely used to manage type 2 diabetes mellitus, but it often leads to several gastrointestinal side effects, particularly with long-term use. Therefore, it is important to find an additional treatment that can work alongside metformin to enhance its effectiveness while reducing these negative effects (1)
The study is a randomized, double-blind, placebo-controlled clinical trial conducted over three months. It involves patients with type 2 diabetes mellitus, with 48 participants completing the trial. The trial aims to evaluate whether a daily dose of 3×10^10 CFU, administered as 2 grams after dinner, of a combination of probiotics—Bifidobacterium animalis lactis Probio-M8, Bifidobacterium animalis lactis V9, Lactic…