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Atogepant was used to prevent migraines
Atogepant 30 mg twice a day and 60 mg once a day showed clinically relevant reductions in mean monthly migraine days (MMDs) across 12 weeks in chronic migraine patients. Both atogepant doses were well tolerated, consistent with the known safety profile of atogepant.
Oral atogepant once daily was effective in reducing the number of migraine days and headache days over a period of 12 weeks. Adverse events included constipation and nausea. Longer and larger trials are needed to determine the effect and safety of atogepant for migraine prevention.
References:
Ailani et al. 2021 N Engl J …