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Understanding the dual role of polyamines in promoting and suppressing tumor growth is crucial for developing targeted therapies that can modulate their levels and activity in the body (7).
Polyamines are organic compounds that play a significant role in various biological processes, including cell growth and differentiation. Their excessive release in the tumor microenvironment can have profound effects on immune regulation and cancer progression. In the tumor microenvironment, the excessive release of polyamines di…