Gut microbiota-bile acid (GM-BA) axis

How the Gut Microbiota–Bile Acid Axis Shapes Liver Health

The gut microbiota–bile acid (GM–BA) axis connects microbial activity with bile acid metabolism and is important to liver function and health. Microbiota-derived bile acids can influence immune responses and metabolic pathways that affect liver graft function (1).

Microbial Bile Acid Pathways and Host Receptor Signaling

Microbial bile-salt hydrolases (BSH), the bai gene pathway, and other enzymes transform bile acids. The resulting changes may affect host FXR a…