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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

AuthorsReferences (Sources)

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Aryl hydrocarbon receptor (AHR) & Endothelial Cells / Endothelium

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Contents

The aryl hydrocarbon receptor (AHR) acts as a critical node for endothelial cell sensing of dietary metabolites in adult mice and human primary endothelial cells
Wiggins et al. 2023 Nature 621: 821-829

Aryl hydrocarbon receptor (AHR) regulates endothelial proliferation
Wiggins et al. 2023 Nature 621: 821-829

Aryl hydrocarbon receptor (AHR) activation promotes vasculoprotective responses in endothelial subtypes
Wiggins et al. 2023 Nature 621: 821-829

Aryl hydrocarbon receptor (AHR) ligands act directly on endothelial cells to promote quiescence and anti-inflammatory programmes
Wiggins et al. 2023 Nature 621: 821-829

Several dietary metabol…

References (Sources)

Aryl hydrocarbon receptor null mice develop cardiac hypertrophy and increased hypoxia-inducible factor-1alpha in the absence of cardiac hypoxia
Thackaberry et al. 2002 Cardiovasc. Toxicol. 2: 263-274
Endothelial sensing of AHR ligands regulates intestinal homeostasis
Wiggins et al. 2023 Nature 621: 821-829
Modulation of Immune Responses by Nutritional Ligands of Aryl Hydrocarbon Receptor
De Juan & Segura 2021 Front Immunol. 12: 645168
Review
Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice
Lahvis et al. 2000 Proc. Natl Acad. Sci. USA 97: 10442-10447
Targeting the aryl hydrocarbon receptor by gut phenolic metabolites: A strategy towards gut inflammation
Pinto et al. 2023 Redox Biol. 61: 102622
Review
The aryl hydrocarbon receptor is required for developmental closure of the ductus venosus in the neonatal mouse
Lahvis et al. 2005 Mol. Pharmacol. 67: 714-720

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