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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Thymic Stromal Lymphopoietin (TSLP)

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Contents

Thymic stromal lymphopoietin (TSLP) is a Type 1 cytokines produced primarily by epithelial cells at barrier surfaces
Ziegler & Artis 2010 Nat. Immunol. 11: 289-293

Thymic Stromal Lymphopoietin (TSLP) is associated with other allergic diseases: food allergy and Eosinophilic esophagitis (EoE)
Roan et al. 2012 J. Leukoc. Biol. 91: 877-886

Expression of Thymic Stromal Lymphopoietin (TSLP) was significantly increased at lesion sites in atopic dermatitis (AD) and [asthma](brain://yE20dWWIDkGEFA9vnFNGpQ/Ast…

References (Sources)

Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: formation of a functional heteromeric complex requires interleukin 7 receptor
Park et al. 2000 J. Exp. Med. 192: 659-670
Distinct signal codes generate dendritic cell functional plasticity
Arima et al. 2010 Sci. Signal. 3: ra4
Human epithelial cells trigger dendritic cell mediated allergic inﬂammation by producing TSLP
Soumelis et al. 2002 Nat. Immunol. 3: 673-680
Sensing the outside world: TSLP regulates barrier immunity
Ziegler & Artis 2010 Nat. Immunol. 11: 289-293
The transcription factor STAT5 is critical in dendritic cells for the development of TH2 but not TH1 responses
Bell et al. 2013 Nat. Immunol. 14: 364-371
Thymic stromal lymphopoietin-mediated STAT5 phosphorylation via kinases JAK1 and JAK2 reveals a key difference from IL-7-induced signaling
Rochman et al. 2010 Proc. Natl. Acad. Sci. USA 107: 19455-19460
TSLP-activated dendritic cells induce an inﬂammatory T helper type 2 cell response through OX40 ligand
Ito et al. 2005 J. Exp. Med. 202: 1213-1223

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Thymic stromal lymphopoietin - Wikipedia