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Hafer et al. (2007) published the effects of Lactulose on Inflammatory bowel disease (IBD) from a prospective, randomised and controlled pilot study with a parallel-group design
The conclusion from the authors was: The findings of the present pilot study indicate that oral lactulose has no beneficial effects in IBD patients in particular with regard to clinical activity, endoscopic score or immunohistochemical parameters. The importance of the beneficial effect of lactulose in UC patients regarding the quality of life needs further evaluation in larger controlled clinical trials
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