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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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nf1 (neurofibromin 1) gene, mutant

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NF1 germline pathogenic variants cause the tumor predisposition syndrome neurofibromatosis type 1.
Giraud et al. 2023 Expert Opinion on Investigational Drugs 32(10): 941-957

NF1 somatic alterations are present in 5% of all human sporadic cancers.
Giraud et al. 2023 Expert Opinion on Investigational Drugs 32(10): 941-957

However, to date, the therapeutic impact of NF1 somatic alterations is poorly investigated.
Giraud et al. 2023 Expert Opinion on Investigational Drugs 32(10): 941-957…

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NF1 alterations in cancers: therapeutic implications in precision medicine
Giraud et al. 2023 Expert Opinion on Investigational Drugs 32(10): 941-957
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7/1/2026

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