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Circadian rhythms play a crucial role in regulating physiological activities by precisely modulating gene expression and biochemical functions.
Circadian rhythm dysfunction is linked to a heightened risk of tumor development, growth, and spread. It also leads to changes in the gut microbiota (GM) and the tumor microenvironment (TME).
All mammals have an internal 24-hour timekeeping system called the circadian clock. It helps the body prepare for predictable daily changes in the environment (). A master clock in the brain's …