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Alfa-toxin (CPA) is a potent exotoxin produced by the seven toxinotypes of the bacterium Clostridium perfringens. This toxin is a zinc-dependent enzyme with both phospholipase C and sphingomyelinase / sphingomyelin phosphodiesterase activities, leading to cytolytic effects.
Alfa-toxin (CPA) is composed of two structural domains and functions as a zinc-containing phospholipase C. It destroys cell membranes, resulting in rapid tissue destruction and impaired blood flow. This toxin is responsible for the life-threatening condition known as [gas gangrene](brai…