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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

AuthorsReferences (Sources)

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Inflammatory Bowel Disease (IBD) & Neurobiological Symptoms

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A growing body of evidence from preclinical, translational, and clinical studies in patients with Inflammatory Bowel Disease (IBD) suggest that dynamic bidirectional interactions within the gut-brain axis contribute to neurobiological symptoms such as stress, depression, anxiety, fatigue, and sleep disturbance
Targownik et al. 2015 Am J Gastroenterol. 110: 1001-1012
Thomann et al. 2017 Sci Rep. 7: 11579
Hashash et al. 2018 J Clin Gastroenterol. 52: 423-430(brain://gawLR--VdE2xNLO_zADVrw/HashashEtAl2018JClinGastroenterol52423430)
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References (Sources)

Depression increases the risk of inflammatory bowel disease, which may be mitigated by the use of antidepressants in the treatment of depression
Frolkis et al. 2019 Gut 68: 1606-1612
Fatigue in IBD: epidemiology, pathophysiology and management
Borren et al. 2019 Nat Rev Gastroenterol Hepatol. 16: 247-259
Intrinsic neural network dysfunction in quiescent Crohn’s disease
Thomann et al. 2017 Sci Rep. 7: 11579
Quality of sleep and coexistent psychopathology have significant impact on fatigue burden in patients with inflammatory bowel disease
Hashash et al. 2018 J Clin Gastroenterol. 52: 423-430
Sleep and inflammatory bowel disease: an important bi-directional relationship
Qazi & Farraye 2019 Inflamm Bowel Dis. 25: 843-852
The relationship among perceived stress, symptoms, and inflammation in persons with inflammatory bowel disease.
Targownik et al. 2015 Am J Gastroenterol. 110: 1001-1012

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7/1/2026

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