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Monticelli et al. (2015) demonstrated that Group 2 ILCs (ILC2) have a protective role in the tissues of the intestinal tract. This function is mediated through the IL33-ILC2s-amphiregulin pathway.
ILC2 expressed amphiregulin after tissue damage of the intestines and activation by IL-33
see also:
[Group 2 ILCs (ILC2) & Interleukin-33 (IL-33)](b…