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Infusions of the short-chain fatty acid (SCFA) acetate into the distal colon have been shown to improve metabolic parameters in men. In this context, we proposed that a combination of rapidly and slowly fermentable fibers could boost acetate production in the distal colon and subsequently enhance metabolic health. To explore this hypothesis, in vitro cultivation studies were conducted using a validated model of the colon to identify fiber mixtures that resulted in high levels of acetate production in the distal colon (1)
It is a randomized clinical basic science trial studying Beta-glucan vs [Beta-glucan + Resistant starch from potatoes (RPS)](brain://9ZM-JjuyekyfyaWBRGKpYA/BetaglucanResi…