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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

AuthorsReferences (Sources)

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Atherosclerosis / Coronary Artery Disease (CAD) / Coronary Heart Disease (CHD) / Ischemic Heart Disease (IHD) & Trimethylamine-N-Oxide (TMAO)

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Contents

Targeting Trimethylamine-N-Oxide (TMAO) could be a novel therapeutic strategy for alleviating atherosclerosis
Jing et al. 2022 Front. Cardiovasc. Med. 9: 864600

In this review, the focus is on the effect of gut microbiota and microbe-derived metabolites, including trimethylamine-N-oxide (TMAO), short-chain fatty acids (SCFAs), and lipopolysaccharide (LPS), on the stability of [atherosclerotic plaque](brain://b…

References (Sources)

Dietary choline or trimethylamine N-oxide supplementation does not inﬂuence atherosclerosis development in Ldlr-/-and Apoe-/-male mice
Aldana-Hernandez etal. 2020 J. Nutr. 150: 249-255
Gut Metabolite Trimethylamine-N-Oxide in Atherosclerosis: From Mechanism to Therapy
Wang et al. 2021v Front Cardiovasc Med. 8: 723886
Review
Gut Microbiota and Atherosclerosis—Focusing on the Plaque Stability
Shen et al. 2021a Front. Cardiovasc. Med. 8: 668532
Review
L-Carnitine intake and high trimethylamine N-oxide plasma levels correlate with low aortic lesions in ApoE(-/-) transgenic mice expressing CETP
Collins et al. 2016 Atherosclerosis 244: 29-37
Trimethylamine N-oxide promotes tissue factor expression and activity in vascular endothelial cells: A new link between trimethylamine N-oxide and atherosclerotic thrombosis
Cheng et al. 2019a Thromb. Res. 177: 110-116
Trimethylamine N-Oxide Promotes Vascular Inflammation Through Signaling of Mitogen-Activated Protein Kinase and Nuclear Factor-κB
Seldin et al. 2016 J Am Heart Assoc. 5: e002767
Trimethylamine-N-oxide (TMAO)-induced atherosclerosis is associated with bile acid metabolism
Ding et al. 2018 Lipids Health Dis. 17: 286

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