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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Capmatinib & Non-Small-Cell Lung Carcinoma (NSCLC) (MET m)

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Capmatinib is a drug approved by the US Food and Drug Administration (FDA) for the treatment of Non-Small-Cell Lung Carcinoma (NSCLC) (MET exon 14) skipping alteration.

Patients with Non-Small-Cell Lung Carcinoma (NSCLC) (MET exon 14) skipping mutations have been shown to benefit from capmatinib therapy, with minimal side effects and better efficacy than traditional chemotherapy
Shah et al. 2020 Oncology & Haematology Review 16(2): 100-10
Clough et al. 2022 Ann Transl Med. 10(23): 1287…

References (Sources)

Capmatinib for the treatment of non-small cell lung cancer
Vansteenkiste et al. 2019
Capmatinib in MET Exon 14–Mutated or MET-Amplified Non–Small-Cell Lung Cancer
Wolf et al. 2020a N Engl J Med 383: 944-957
MET Exon 14 Skipping Alterations in Non-small Cell Lung Carcinoma—Current Understanding and Therapeutic Advances
Shah et al. 2020 Oncology & Haematology Review 16(2): 100-10
Review
Non-small cell lung cancer with MET exon 14 skip mutation: case report
Clough et al. 2022 Ann Transl Med. 10(23): 1287

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Capmatinib & Non-Small-Cell Lung Carcinoma (NSCLC) (MET m)

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