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The lesser known fecal protein chromogranin A (CgA) has only been used as biomarker for Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS) in scientific research settings
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Chromogranin A (CgA) is a member of the granite peptides, which are secreted in nervous, endocrine, and immune cells under stress. In the gut, CgA is secreted by entero-endocrine cells and shows co-expression with serotonin, suggesting it has a role in the gut-brain axis, and elevated levels of fecal CgA have been associated with IBS and with ulcerativ…