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Objective in this consensus statement, an international panel of experts deliver their opinions on key questions regarding the contribution of the human microbiome to carcinogenesis.
Design international experts in oncology and/or microbiome research were approached by personal communication to form a panel. a structured, iterative, methodology based around a 1-day roundtable discussion was employed to derive expert consensus on key questions in microbiome-oncology research. results Some 18 experts convened for the roundtable discussion and five key questions were identified regarding: (1) the relevance of dysbiosis/an altered gut microbiome to carcinogenesis; (2) potential mechanisms of microbiotainduced carcinogenesis; (3) conceptual frameworks describing how the human microbiome may drive carcinogenesis; …