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Iron levels play a crucial role in the activity of Catechol-O-methyltransferase (COMT) inhibitors. Extracellular iron can inactivate Catechol-O-methyltransferase (COMT) inhibitors, thereby aiding bacterial survival. Conversely, low intracellular iron levels can protect bacteria from the effects of Catechol-O-methyltransferase (COMT) inhibitors.
see also:
Drugs / Medications & Gut microbiota
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