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Systemic sclerosis (SSc) is an autoimmune disease that causes a buildup of collagen in skin and internal organs.
Scleroderma / Systemic sclerosis (SSc) is a complex orphan disease characterized by early inflammatory features, vascular hyper-reactivity, and fibrosis of the skin and internal organs. Despite progress in understanding its pathogenesis, no disease-modifying drug significantly impacts its natural history.
Systemic sclerosis (SSc) has the highest case-specific mortality of all connective tissue diseases. Its underlying disease mechanism affects several organs and remains incompletely understood.
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