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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Inflammation / Inflammatory Diseases & Takeda G-Protein-Coupled Receptor 5 (TGR5, BG37, GBPAR1)

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Takeda G-protein-coupled Receptor 5 (TGR5, BG37, GBPAR1) expression increases in rodent models of colitis and Crohn’s disease
Cipriani et al. 2011 PLoS ONE 6: e25637

The eﬀects on inflammation and dyslipidemia in atherosclerosis could be mediated by the bile acid receptors TGR5 and [FXR](brain://tTjoT4Lmxk24SppKEhsEkw/Farnesoid…

References (Sources)

Gut Microbiota in Hypertension and Atherosclerosis: A Review
Verhaar et al. 2020 Nutrients 12: 2982
Review
The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis
Cipriani et al. 2011 PLoS ONE 6: e25637
The G-protein coupled bile acid receptor Gpbar1 (TGR5) negatively regulates hepatic inflammatory response through antagonizing Nuclear Factor κB
Wang et al. 2011a Hepatology. 54: 1421-1432

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Inflammation / Inflammatory Diseases & Takeda G-Protein-Coupled Receptor 5 (TGR5, BG37, GBPAR1)

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