Chemotherapy (CT) & Breast Cancer / Mammacarcinoma

Chemotherapy may be given before surgery as neoadjuvant therapy to shrink a tumor, improve the chance of breast-conserving surgery, and sometimes reduce the extent of lymph-node surgery. It may be given after surgery as adjuvant therapy to destroy remaining cancer cells and lower recurrence risk (1). Chemotherapy may be indicated in higher-risk situations such as triple-negative breast cancer, HER2-positive disease, grade 3 tumors, lymph node involvement, inflammatory breast cancer, or large tumors (1).

Breast-cancer chemotherapy often uses combinations rather than a single drug. …