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Yang et al. (2020) identified the human gut microbial species Bacteroides ovatus as the species that best induced gut IgA production by mono-colonizing mice. The high IgA-inducing Bacteroides ovatus strains preferentially elicited more IgA production in the large intestine through the T cell-dependent B cell-activation pathway. This induction varied bimodally across different Bacteroides ovatus strains.
see also:
Bacteria & Secreted Immunoglobulin A (sIgA) / IgA
Gut microbiota & Secreted Immunoglobulin A (sIgA) / IgA