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Circular RNAs (circRNAs) have been implicated in the immune microenvironment of various cancers, including digestive cancers and hepatocellular carcinoma (HCC). They can modulate immune responses through several mechanisms:
These actions can affect the immune microenvironment, promoting tumor progression and immune evasion. For instance, exosomal Circular RNAs (circRNAs) derived from Hepatocellular Carcinoma (HCC) cells can carry signals that modulate immune cell activation and promote the expre…