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NLRC1 / NOD1 (NOD-like receptor family CARD Domain-Containing Protein 1) plays a critical role in the production of Beta-defensins (1). Gamma-glutamyldiaminopimelic acid (iE-DAP), a breakdown product of Gram-negative bacteria's cell walls, enters the cell and encounters NOD1 intracellularly. NFKB is activated via various intermediate stages, thereby releasing Beta-defensins
(1)
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