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The Brain-Gut-Microbiome-Axis / Gut-Brain Axis (MGBA) may link affective symptoms, sleep disturbances, and chronic constipation. Human observational studies, Mendelian randomization analyses, animal models, and preliminary interventional studies indicate that changes in gut microbial composition and function might contribute to these conditions (17).
They may play a role in the development of mental illnesses, including depressive disorders (1, 2, 3, 4, 5, 6). The ingestion of a Lactobacillus strain influences emotional behavior and the expression of [central GABA receptors](brain://Ip…