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Mitogen-activated protein kinase kinase, also known as MEK, is an enzyme with dual-specificity kinase activity (can act as both tyrosine kinase and serine/threonine kinase). It functions by phosphorylating mitogen-activated protein kinase (MAPK).
Mitogen-activated protein kinase kinases / MEKs have one main substrate: Extracellular signal-regulated kinases (ERKs)
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