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Synbiotics can suppress tumorigenesis caused by colitis (e.g. dextran sodium sulfate model) in animal models and reduce the mortality of mice
It is possible that Lactobacillus casei and Bifidobacterium breve in the fecal microbiota associated with synbiotic treatment contributed to the observed effects.
Synbiotics may also potentially reduce cancer risk factors in patients with polyps and colon cancer, and they can modulate the metabolic pathways of the intestinal microbiota and inhibit the development of colon tumors by suppressing genes such as c-myc and PCNA
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