Diarrhea / Diarrhoea (antibiotic-induced)

Systemic antibiotic therapy frequently causes antibiotic-associated diarrhoea (AAD).
Cremonini et al. 2002 Aliment Pharmacol Ther 16: 1461-1467

Diarrhea is a common adverse event of antibiotic medication. The occurrence of diarrhea is probably due to disruption of the normal gastrointestinal microbiota. Clostridium difficile infection is the most serious form of antibiotic-associated diarrhea (AAD).
Cheng et al. 2020 World J Clin Cases 8(8): 1361-1384

In the human gut microbiome, Clostridioides (Clostridium) difficile is present, but the use of broad-spectrum antibiotics, especially third-generation cephalosporins, has turned it into a major cause of antibiotic-associated diarrhea.
de Lalla et al. 1989 J Antimicrob Chemother 23: 623-631
Knight & Riley 2019 Front Public Health 7: 164

see aso:
Cephalosporins & Clostridioides (Clostridium) difficile