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There is still no clinically available disease-modifying therapy for osteoarthritis (OA).
The development of drug delivery systems (DDS)-based intra-articular disease-modifying osteoarthritis drugs have not been successful so far.
To date, all pharmacologic treatments for Osteoarthritis / Arthrosis are directed toward pain management.
Inducible nitric oxide synthase as a target for osteoarthritis…