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There is significant functional redundancy among virulence factors, which complicates therapeutic targeting. This redundancy includes overlapping toxin activities and alternative regulatory pathways, such as two-component systems and SarA family proteins. These factors contribute to the pathogen's resilience against therapeutic interventions.
Salmonella's virulence factors and antibiotic treatments both contribute to the pathogen's expansion by depleting butyrate-producing Clostridia. This depletion increases epithelial [oxygena…