Bacteroides fragilis & Colitis / Intestinal Inflammation

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Bacteroides fragilis triggers Toll-like receptor 2 signaling in Tregs, subsequently suppressing T-helper type 17 cell (Th17) responses (1).

PSA expressing B…

A microbial symbiosis factor prevents intestinal inflammatory disease
Mazmanian et al. 2008
Baseline human gut microbiota profile in healthy people and standard reporting template
King et al. 2019
Inducible Foxp3+ Treg-cell development by a commensal bacterium of the intestinal microbiota
Round & Mazmanian 2010
Microbiota-mediated colonization resistance against intestinal pathogens
Buffie & Pamer 2013
The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota
Round et al. 2011
The yin yang of bacterial polysaccharides: Lessons learned from B. fragilis PSA
Surana & Kasper 2012 Immunol Rev. 245: 13–26

11/5/2026