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Ferroptosis is a special form of regulated cell death. It occurs when the balance of certain chemical processes inside a cell is disrupted. As a result, many fats in the cell membrane are damaged. Eventually, the cell membrane breaks down, and the cell dies quickly.
Ferroptosis can be induced in various ways. These include Gpx4 deletion, S100A4 inhibition, and cancer nanovaccines. These methods improve the tumor microenvironment. They work well with immune checkpoint inhibitors. This is seen in liver cancer and melanoma models
Ma et al. 202…