Antiviral Immunity & RNA regulatory mechanisms

From the initial sensing of viral nucleotides by pattern recognition receptors to the induction of type I and III interferons (IFN), the upregulation of antiviral effector proteins, and the resolution of the inflammatory response, each step of innate immune signaling is under tight control. While innate immunity is often associated with broad regulation at the level of gene transcription, RNA-centric post-transcriptional processes have emerged as critical mechanisms for ensuring a proper antiviral response.
Gokhale et al. 2021a Immunological Reviews 304: 77-96

The diverse RNA regulatory mechanisms that modulate the innate antiviral [immune response](brain://5QFzqPH_7kiBWucrMxK3ow/Immune…