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Specific microbiota members such as Faecalibaculum rodentium alter epithelial homeostasis by increasing epithelial turnover rate, crypt proliferation, and primary histocompatibility complex class II (MHC class II) expression.
Cao et al. 2022 Cell Host & Microbe 30: 1295-1310
F. rodentium decreases enterocyte expression of the retinoic acid-producing enzymes Adh1, Aldh1a1, and Rdh7, thereby reducing retinoic acid…