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Unexpectedly, we discovered that pasteurization of Akkermansia muciniphila MucT TM enhanced its capacity to reduce fat mass development, insulin resistance and dyslipidemia in mice. We demonstrated that Amuc_1100, a specific protein isolated from the outer membrane of A. muciniphila, interacts with Toll-like receptor 2, is stable at temperatures used for pasteurization, improves the [g…