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Transglutaminase 2 (TG2) has been associated with numerous neurological disorders, including neurodegenerative diseases, multiple sclerosis, and CNS injury.
Transglutaminase 2 (TG2) can "cross-link" proteins into insoluble aggregates. However, Transglutaminase 2 (TG2) also regulates numerous cellular processes that might contribute to a particular disease.
At present, it seems unlikely that inhibition of Transglutaminase 2 (TG…