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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

AuthorsReferences (Sources)

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Carcinogenesis / Oncogenesis / Tumorigenesis & Clonorchis sinensis

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The relationship between Clonorchis sinensis (CS) infection and carcinogenesis, specifically cholangiocarcinoma (CCA), is well-documented and complex, involving multiple biological mechanisms and pathways. Clonorchis sinensis, a liver fluke, is classified as a Group 1 carcinogen by the International Agency for Research on Cancer (IARC) due to its strong association with the development of cholangiocarcinoma, a type of liver cancer affecting the bile ducts.
Wang et al. 2011a Genome Biol 12: R107
Hong & Fang 2012 Parasitol Int. 61(1): 17-24
Huang et al. 2013 PLoS One 8(1): e54732
Uddin et al. 2015 PLoS Negl Trop Dis 9(8): e0004008
Kim et al. 2016a BMB Rep. 49(11): 590-597
Machicado & Marco…

References (Sources)

Carcinogenesis associated with parasites other than Schistosoma, Opisthorchis and Clonorchis: A systematic review
Machicado & Marcos 2016 Int J Cancer 138(12): 2915-21
Review
Clinical Characteristics of Clonorchis sinensis-Associated Cholangiocarcinoma: A Large-Scale, Single-Center Study
Chang et al. 2021d Front Med (Lausanne) 8: 675207
Clonorchis sinensis and clonorchiasis, an update
Hong & Fang 2012 Parasitol Int. 61(1): 17-24
Review
Clonorchis sinensis excretory-secretory products increase malignant characteristics of cholangiocarcinoma cells in three- dimensional co-culture with biliary ductal plates
Won et al. 2019 PLoS Pathog 15(5): e1007818
Identification and Analysis of the Tegument Protein and Excretory-Secretory Products of the Carcinogenic Liver Fluke Clonorchis sinensis
Shi et al. 2020e Front. Microbiol. 11: 555730
Involvement of PSMD10, CDK4, and Tumor Suppressors in Development of Intrahepatic Cholangiocarcinoma of Syrian Golden Hamsters Induced by Clonorchis sinensis and N- Nitrosodimethylamine
Uddin et al. 2015 PLoS Negl Trop Dis 9(8): e0004008
The carcinogenic liver fluke, Clonorchis sinensis: new assembly, reannotation and analysis of the genome and characterization of tissue transcriptomes
Huang et al. 2013 PLoS One 8(1): e54732

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