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CAR-NK (chimeric antigen receptor-natural killer) cells are a promising next-generation type of cellular immunotherapy that involves engineering natural killer (NK) cells to express Chimeric antigen receptors (CARs), enabling them to recognize and kill cancer cells.
They offer several advantages, such as a lower risk of cytokine release syndrome (CRS), neurotoxicity, and graft-versus-host disease (GVHD), and they do not require human leukocyte antigen (HLA) compatibility.
CAR-NK cells have demonstrated efficacy in preclinical and clinical studies for a variety of cancers, including [he…