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GM influences the effectiveness and side effects of cancer therapies, especially immunotherapy. Research shows that bacteria producing short-chain fatty acids (SCFAs), Akkermansia muciniphila, and certain Lachnospiraceae and Ruminococcaceae families improve responses to [immune checkpoint inhibitors (ICIs)](brain://togqPNZxkES9J5a2SgjWQQ/ImmuneCheckpointInhib…