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Group 2 ILCs (ILC2) are crucial tissue-resident immune cells known for their production of type 2 cytokines, such as Interleukin-5 (IL-5) and IL-13, in response to alarmins like Interleukin-13 (IL-13). These cytokines play a significant role in various immune processes.
One of the key functions of ILC2-derived Interleukin-5 (IL-5) is its critical support for the survival and maturation of B-1 cell. B-1 cell are responsible for producing natural IgM antibodies, which are essential in [defending against pathogens](brain://3jwwruycQ0e64…