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In the context of Ripretinib and GIST (gastrointestinal stromal tumors), Ripretinib is approved by the FDA for the treatment of advanced GIST (gastrointestinal stromal tumors) in adult patients who have received prior treatment with three or more kinase inhibitors, including imatinib. The EMA (European Medicines Agency) has also authorized ripretinib for a similar indication in advanced GIST as a fourth-line therapy (1, 2, 5).
The clinical …