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The study investigates the effects of fructooligosaccharides (FOS) vs galactooligosaccharides (GOS) on glucose metabolism and gut microbiota. Conducted as a randomized double-blind cross-over trial with 35 adults, participants consumed 16 g/day of FOS and GOS for 14 days. Results showed that high-dose prebiotics adversely affected glucose metabolism, with significant changes observed in oral glucose tolerance test (OGTT) and fasting glucose levels. Both FOS and GOS increased Bifidobacterium but decreased [butyrate-producing bacteri…