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The FDA approved Xenical TM (orlistat 120 mg) in 1999 as a prescription product for obesity management. It is intended to be used alongside a reduced-calorie diet and aims to reduce the risk of weight regain after prior weight loss. In 2007, the FDA also approved Alli TM (orlistat 60 mg) for over-the-counter weight loss. This product is designed for overweight adults aged 18 years and older and should be used in conjunction with a reduced-calorie, low-fat diet (1)
The European Medicines Agency (EMA) authorisation for Alli TM confirms that orlistat is a…