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In general, bexarotene is an active and reasonable chemoprevention and treatment for various cancers and its combination regimen with other cytotoxic agents or targeted drugs may significantly enhance efficacy and at the same time reduce toxicity due to their nonoverlapping side effects.
However, only a subpopulation of bexarotene treated patients benefited from bexarotene administration in most cases.
The level of [Retinoid X r…