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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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MGL & MUCIN-1 (MUC1) / CA15-3

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Since activation of MGL without TLR induction can lead to anergy, binding of MUC1-STn to MGL might be partially responsible for some of the characteristics of Sialyl-Tn (STn) / Neu5Acα2-6GalNAc-O-Ser/Thr-expressing tumors
Beatson et al. 2015

see also:
Breast Cancer / Mammacarcinoma & Sialyl-Tn (STn) / Neu5Acα2-6GalNAc-O-Ser/Thr
Endometrial Cancer (EC) & Sialyl-Tn (STn) / Neu5Acα2-6GalNAc-O-Ser/Thr
[Ovarian Cancer & Sialyl-Tn (STn) / Neu5Acα2-6GalNAc-O-Ser/Thr](b…

References (Sources)

The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL
Beatson et al. 2015

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7/1/2026

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MGL & MUCIN-1 (MUC1) / CA15-3

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