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Antibiotics reversed the metabolic effects of Fexamarine
The intestine-restricted Fexamarine agonist fexaramine stimulated GLP-1 secretion and hepatic insulin sensitivity
Fexaramine treatment increased lithocholic acid content and bile acid hydrophobicity in gallbladder and intestinal bile
Fexaramine increased lithocholic acid synthesis and altered bile acid composition.
Fexaramine did not affec…