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Nuclear factor erythroid 2-related factor 2 (NFE2L2) has been regarded as a double-edged sword and elevated Nuclear factor erythroid 2-related factor 2 (NFE2L2) expression have been detected in cancer tumors and over-activation has been reported to promote oncogenesis
The relationship between Carcinogenesis and Nuclear factor erythroid 2-related factor 2 (NFE2L2) is that Nuclear factor erythroid 2-related factor 2 (NFE2L2) activation provides cytoprotection against cancer initiation. Nuclear factor erythroid 2-related factor 2 (NFE2L2) is critical in the maintenance of redox, metabolic, and protein homeostasis, as well as the regulation of inflammation. It acts as a transcription factor that activates the expression of genes involved in antioxidant …