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IL-1 Receptor Type II (IL-1R2) is released from the cell surface and binds precursor and mature forms of Interleukin-1 (IL-1) beta, acting as a decoy receptor and inhibitor of Interleukin-1 (IL-1) beta function, as IL-1 Receptor Type II (IL-1R2) binds Interleukin-1 (IL-1) but cannot bind MyD88 and does not transduce any signal.
Stylianou & Saklatvala 1998 Int J Biochem Cell…